Our AAM tool takes known protein structures either from X-Ray Diffraction / Cryo-Electron Microscopy or computational methods like AlphaFold2, maps single nucleotide variants (SNVs) to the structure, and filters them based on a Relative Solvent Accessibility threshold. The SNVs are supplied by the user and are typically found in various consortiums, public datasets, or other sources. This workflow allows for quick analysis of biological hotspots, key mutated residues, and finding mutations in areas of interest. These mutations can be reproduced in vivo to allow for drug studies, gain / loss of function studies, mechanism studies, and more.